What tissues are affected by psoriasis?
Psoriasis can appear anywhere on the body, even on the eyelids, ears, lips, skin folds, hands, feet, and nails. Plaques can be a few small patches or can affect large areas. It’s possible to have psoriasis plaques and scales in more than one location on the body at a time.
How does psoriasis affect epithelial tissue?
Dermatological psoriasis symptoms result from exaggerated and disordered epidermal cell proliferation and keratinization. Dysregulated interactions of the innate and adaptive immune system in skin epithelium and connective tissue result in inappropriate and damaging inflammation.
What are the areas of skin where psoriasis commonly occurs?
Psoriasis is a skin disorder that causes skin cells to multiply up to 10 times faster than normal. This makes the skin build up into bumpy red patches covered with white scales. They can grow anywhere, but most appear on the scalp, elbows, knees, and lower back.
Is psoriasis an autoimmune connective tissue disease?
Psoriasis is an autoimmune chronic inflammatory skin disease that is common in Spain. Connective tissue diseases are a heterogeneous group of conditions characterized by the abnormal function or structure of one or more of the elements that make up connective tissue.
What is the root cause of psoriasis?
Psoriasis occurs when skin cells are replaced more quickly than usual. It’s not known exactly why this happens, but research suggests it’s caused by a problem with the immune system. Your body produces new skin cells in the deepest layer of skin.
What type of hypersensitivity reaction is psoriasis?
Introduction. Contact dermatitis (CD) and psoriasis are common skin disorders, which represent two distinct pathologies. The former is mediated by delayed-type IV hypersensitivity reaction and the latter is less understood, though Th1 and Th17 cells are thought to play an important role in its pathophysiology.